B-Basic in Delft is a consortium of universities, research institutions and industry. The programme focuses on the development of new bio-based production concepts for the chemical (and energy) industry which are rooted in the current explosive increase in fundamental insights in molecular biology through the genomics revolution, combined with advanced bioprocess technology and existing chemical knowledge. Research in the B-Basic optimally benefits from the latest breakthroughs in genomics research by using the new insights to develop processes that can convert biomass into chemicals using biocatalysts as microorganisms and enzymes. B-Basic is an independent NWO-ACTS (http://www.nwo.nl/nwohome.nsf/pages/NWOA_6P69LY_Eng) programme. The scientific and business director are provided by the Delft University of Technology. B-basic cooperates closely with Kluyver centre for genomics.